| Date | Location | Result | |
| Nov 20, 2010 | Conway, S.C. | Coastal Carolina 70, Charleston Southern 3 | Box score |
| Nov 13, 2010 | Charleston, S.C. | Charleston Southern 42, Presbyterian Coll. 39 | Box score |
| Nov 06, 2010 | Lexington, KY | Kentucky 49, Charleston Southern 21 | Box score |
| Oct 30, 2010 | Stony Brook, N.Y. | Stony Brook 41, Charleston Southern 21 | Box score |
| Oct 23, 2010 | Charleston, S.C. | VMI 34, Charleston Southern 16 | Box score |
| Oct 16, 2010 | Charleston, S.C. | Gardner-Webb 35, Charleston Southern 25 | Box score |
| 10-09-10 | Lynchburg, Va. | Liberty 44, Charleston Southern 20 | Box score |
| Sep 25, 2010 | Honolulu, HI | Hawai`i 66, Charleston Southern 7 | Box score |
| Sep 18, 2010 | Charleston, S.C. | Charleston Southern 28, Mars Hill 14 | Box score |
| Sep 11, 2010 | Charleston, S.C. | Wofford 34, Charleston Southern 23 | Box score |
| Sep 04, 2010 | Charleston, S.C. | Charleston Southern 41, NGU 31 | Box score |